Holy Ghost! is an American synthpop duo from Brooklyn, New York City, consisting of Nick Millhiser and Alex Frankel.
Millhiser and Frankel both grew up on the Upper West Side of New York City and attended elementary school together. They were later part of a hip hop group called Automato. Automato's debut album was produced by James Murphy and Tim Goldsworthy of DFA. After the release of the album, Automato "kind of fell apart". However, Millhiser and Frankel kept working on music. Initially it was going to be more hip hop work, but decided to create music with vocals and poppier arrangements.