Differences in genetic (inherited) makeup among us affect what the body does to a drug and what the drug does to the body. The study of genetic differences in the response to drugs is called pharmacogenomics.
Because of their genetic makeup, some people process (metabolize) drugs slowly. As a result, a drug may accumulate in the body, causing toxicity. Other people metabolize drugs so quickly that after they take a usual dose, drug levels in the blood never become high enough for the drug to be effective.
In this talk, Ravi Ponnuusmay, a neuroscientist, psychopharmacologist and researcher at Stanford University walks us through the topic, how genes affect our response to drugs and will explore it in specific cases as examples.
Ravi's Bio:
Dr.Ravi Ponnusamy is a Health Scientist at VA Palo Alto/Stanford University School of Medicine. He received his PhD from the Department of Psychopharmacology at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. After receiving PhD, he joined UCLA Brain Research Institute to do his postdoctoral research on fear and anxiety disorders including Post Traumatic Stress Disorders (PTSD). Later Ravi directed neurobehavioral core research laboratories at UCLA and Gladstone Institutes/UCSF and collaborated with a wide variety of laboratories to prevent, reduce or reverse cognitive dysfunctions in neurological and psychiatric diseases. He has published numerous high-profile papers in the fields of PTSD, Traumatic Brain Injury, Down Syndrome, and Alzheimer’s disease. He advises SPARK translational program at Stanford University and teaches Psychopharmacology at California State University East Bay, Hayward.
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Because of their genetic makeup, some people process (metabolize) drugs slowly. As a result, a drug may accumulate in the body, causing toxicity. Other people metabolize drugs so quickly that after they take a usual dose, drug levels in the blood never become high enough for the drug to be effective.
In this talk, Ravi Ponnuusmay, a neuroscientist, psychopharmacologist and researcher at Stanford University walks us through the topic, how genes affect our response to drugs and will explore it in specific cases as examples.
Ravi's Bio:
Dr.Ravi Ponnusamy is a Health Scientist at VA Palo Alto/Stanford University School of Medicine. He received his PhD from the Department of Psychopharmacology at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. After receiving PhD, he joined UCLA Brain Research Institute to do his postdoctoral research on fear and anxiety disorders including Post Traumatic Stress Disorders (PTSD). Later Ravi directed neurobehavioral core research laboratories at UCLA and Gladstone Institutes/UCSF and collaborated with a wide variety of laboratories to prevent, reduce or reverse cognitive dysfunctions in neurological and psychiatric diseases. He has published numerous high-profile papers in the fields of PTSD, Traumatic Brain Injury, Down Syndrome, and Alzheimer’s disease. He advises SPARK translational program at Stanford University and teaches Psychopharmacology at California State University East Bay, Hayward.
Differences in genetic (inherited) makeup among us affect what the body does to a drug and what the drug does to the body. The study of genetic differences in the response to drugs is called pharmacogenomics.
Because of their genetic makeup, some people process (metabolize) drugs slowly. As a result, a drug may accumulate in the body, causing toxicity. Other people metabolize drugs so quickly that after they take a usual dose, drug levels in the blood never become high enough for the drug to be effective.
In this talk, Ravi Ponnuusmay, a neuroscientist, psychopharmacologist and researcher at Stanford University walks us through the topic, how genes affect our response to drugs and will explore it in specific cases as examples.
Ravi's Bio:
Dr.Ravi Ponnusamy is a Health Scientist at VA Palo Alto/Stanford University School of Medicine. He received his PhD from the Department of Psychopharmacology at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. After receiving PhD, he joined UCLA Brain Research Institute to do his postdoctoral research on fear and anxiety disorders including Post Traumatic Stress Disorders (PTSD). Later Ravi directed neurobehavioral core research laboratories at UCLA and Gladstone Institutes/UCSF and collaborated with a wide variety of laboratories to prevent, reduce or reverse cognitive dysfunctions in neurological and psychiatric diseases. He has published numerous high-profile papers in the fields of PTSD, Traumatic Brain Injury, Down Syndrome, and Alzheimer’s disease. He advises SPARK translational program at Stanford University and teaches Psychopharmacology at California State University East Bay, Hayward.
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Because of their genetic makeup, some people process (metabolize) drugs slowly. As a result, a drug may accumulate in the body, causing toxicity. Other people metabolize drugs so quickly that after they take a usual dose, drug levels in the blood never become high enough for the drug to be effective.
In this talk, Ravi Ponnuusmay, a neuroscientist, psychopharmacologist and researcher at Stanford University walks us through the topic, how genes affect our response to drugs and will explore it in specific cases as examples.
Ravi's Bio:
Dr.Ravi Ponnusamy is a Health Scientist at VA Palo Alto/Stanford University School of Medicine. He received his PhD from the Department of Psychopharmacology at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. After receiving PhD, he joined UCLA Brain Research Institute to do his postdoctoral research on fear and anxiety disorders including Post Traumatic Stress Disorders (PTSD). Later Ravi directed neurobehavioral core research laboratories at UCLA and Gladstone Institutes/UCSF and collaborated with a wide variety of laboratories to prevent, reduce or reverse cognitive dysfunctions in neurological and psychiatric diseases. He has published numerous high-profile papers in the fields of PTSD, Traumatic Brain Injury, Down Syndrome, and Alzheimer’s disease. He advises SPARK translational program at Stanford University and teaches Psychopharmacology at California State University East Bay, Hayward.
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