The University Club of San Francisco is housed in a historic and architecturally significant Clubhouse, designed by local architects Walter Bliss and William Faville, and built shortly after the 1906 earthquake. The Clubhouse is distinguished in the Nob Hill neighborhood with an Italianate style and by its use of brickwork rather than the stone facades or "gingerbread" styles. This was deemed to be more suitable for a "university club" because it evoked the ideal of the renaissance man to which higher education strived for.